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110 signs/symptoms table # Sign or Symptom Typical Frequency Reference 1 Erythema migrans rash Common Steere AC, et al. N Engl J Med. 2001;345(2):115-125. 2 Expanding rash Common Wormser GP, et al. Clin Infect Dis. 2006;43(9):1089-1134. 3 Central clearing rash Common Hu L. Ann Intern Med. 2016;164(9):ITC65-ITC80. 4 Warmth at rash site Common CDC. Signs

1. Erythema Migrans Rash Reference: Steere AC, et al. The clinical evolution of Lyme arthritis. Ann Intern Med. 1983;99(1):76-82. Reference: Wormser GP, et al. The clinical assessment, treatment, and prevention of Lyme disease. Clin Infect Dis. 2006;43(9):1089-1134. 2. Expanding Annular Rash Reference: Steere AC, et al. Lyme disease. N Engl J Med. 2001;345(2):115-125. 3. Central

A newly published study in the Journal of Clinical Microbiology puts concrete data behind a long recognized problem in Lyme disease care. The research, supported by the Bay Area Lyme Foundation and based on data from the Lyme Disease Biobank, found that FDA-cleared testing methods miss between 64 and 78 percent of early Lyme cases.

Below is a 50-item Borrelia debris / inflammatory-particle master list. I am separating two different scientific questions: A. Has the material actually been shown to persist after Borrelia loses viability or after antibiotic treatment? B. Is the molecule a Borrelia component capable of provoking inflammation if released as debris? Only a subset has strong direct