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To our knowledge, this is the first study to examine the effectiveness of a dose increase of SAMe for patients with MDD who failed to respond to an initial dose. While there were no significant differences in effectiveness among SAMe 3,200 mg/day, escitalopram 20 mg/day, and placebo, increased doses of SAMe and of escitalopram provided […]

Durante 34 años, el Dr. James Schaller ha sido pionero en tratamientos para la depresión resistente, apoyándose en su amplia formación tanto en psiquiatría de adultos como infantil. Junto a su compañera de investigación, Kimberly Mountjoy (MS), redactaron este libro para abordar las lagunas significativas existentes en la literatura actual. Sus experiencias personales con la depresión impulsan su

USE LIMP OILS OR ESSENTIAL VOLATILE OILS? Antibiotics Are Useless I was stunned when top LL MDs recommended a combination of a few oils to kill biofilms. Their certainty was contagious. Their excellence as doctors certainly made me listen and use their advice.   Then I thought back to our 2000–2020 research on biofilms and our #1 reference

Most physicians never think of biofilms, despite their being the normal state of bacterial and fungal infections. So people with these infections relapse in a season, a few years or ten years.   Note the image: Two medicines in the picture are utterly useless as they attack from above.    Why? They cannot break through the biofilm. 

Background Neuropathic pain is a difficult to treat disorder arising from central or peripheral nervous system lesions. The etiology of neuropathic pain consists of several overlapping pathways converging into an exaggerated pain state with symptoms such as allodynia and hyperalgesia. One of these pathways involves activation of spinal cord microglia and astrocytes, which drive and

Bacteriophages are viruses that infect bacteria and typically follow either a lytic or lysogenic life cycle. In the lytic cycle, a phage attaches to a host cell, injects its genome, redirects host metabolism to produce progeny, and lyses the cell to release new virions. This rapid bactericidal process underlies their application as antimicrobial agents [49,50]. Host

Acute Onset and Episodic Changes in Behavior Clinical outcome is characterized by the rapid and dramatic onset of OCD plus tics. The beginning of specific symptoms can usually be assigned to a particular day or week, confirming that the onset is relatively rapid and obvious. The prolonged duration of the streptococcal infection could worsen the

For 34 years, Dr. James Schaller has been pioneering treatments for hard-to-treat depression, drawing on extensive training in both adult and child psychiatry. Alongside his research partner, Kimberly Mountjoy, MS, they authored this book to address significant gaps in existing literature. Their personal experiences with depression fuel their dedication to helping others, reflected in their

The treatment of many tick, flea, and biting fly infections often require treatment of severe insomnia. The most effective medications are strong. Are there any mild options? Several herbs can help alleviate insomnia by promoting relaxation and improving sleep quality, including Valerian, Chamomile, and Passionflower. Key Herbs for Insomnia Valerian Root: Valerian is one of the most widely used herbs for insomnia. It contains compounds that have sedative effects, helping to calm the nervous system and reduce the time it takes to fall asleep. Studies have shown that valerian can improve sleep quality, especially in individuals with sleep disturbances. Chamomile: Known for its gentle sedative properties, chamomile is often consumed as a tea before bedtime. It contains apigenin, a flavonoid that binds to brain receptors to promote relaxation and sleep. Chamomile is particularly effective for those whose insomnia is linked to stress or digestive issues. Passionflower: This herb is known for its calming effects on the mind. Passionflower can help reduce anxiety and improve sleep quality, making it a great option for those struggling with insomnia. Lemon Balm: A member of the mint family, lemon balm has a pleasant lemony scent and is known for its ability to reduce anxiety and promote sleep. It can be consumed as a tea or in tincture form. California Poppy: This herb has mild sedative properties and can help ease the transition into sleep. It is often used in herbal formulations for insomnia. Hops: Commonly associated with beer, hops also have sedative effects. Research has shown that hops can improve sleep quality and reduce anxiety levels. Lavender: Known for its calming aroma, lavender can help reduce anxiety and improve sleep quality. Inhaling lavender essential oil or using it in a bath can promote relaxation before bedtime. How to Use These Herbs Teas: Many of these herbs can be brewed into teas. For example, valerian, chamomile, and passionflower teas are popular choices before bed.