Dr James Schaller
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Autism and Lyme

First off, since we know that deer ticks and common fleas and their feces can spread a wide range of infections, and that deer ticks inject an infectious soup into a mother or small child sitting on deer tick filled grass, we should not spend our time only on one Tick-borne infection, but all of them. We also know that the massively under diagnosed Bartonella bacteria which attach to Red Blood Cells and enter blood vessel walls can damage neurons, and may be far more common then Lyme, should also not be ignored. An update on Bartonella basics can be found in my article: www.medscape.com/viewarticle/562276. An update on Babesia can be found in my textbook on Amazon.com and other stores.

New Useful Lyme and Mycoplasma Article and Autism

"The association between tick-borne infections, Lyme borreliosis and autism spectrum disorders"

By Robert C. Bransfield, Jeffrey S. Wulfman, William T. Harvey and Anju I. Usman IN PRESS for Medical Hypothesis

Summary

Chronic infectious diseases, including tick-borne infections such as Borrelia burgdorferi may have direct effects, promote other infections and create a weakened, sensitized and immunologically vulnerable state during fetal development and infancy leading to increased vulnerability for developing autism spectrum disorders. A dysfunctional synergism with other predisposing and contributing factors may contribute to autism spectrum disorders by provoking innate and adaptive immune reactions to cause and perpetuate effects in susceptible individuals that result in inflammation, molecular mimicry, kynurenine pathway changes, increased quinolinic acid and decreased serotonin, oxidative stress, mitochondrial dysfunction and excitotoxicity that impair the development of the amygdala and other neural structures and neural networks resulting in a partial Kluver-Bucy Syndrome and other deficits resulting in autism spectrum disorders and/or exacerbating autism spectrum disorders from other causes throughout life.

Support for this hypothesis includes multiple cases of mothers with Lyme disease and children with autism spectrum disorders; fetal neurological abnormalities associated with tick-borne diseases; similarities between tick-borne diseases and autism spectrum disorder regarding symptoms, pathophysiology, immune reactivity, temporal lobe pathology, and brain imaging data; positive reactivity in several studies with autistic spectrum disorder patients for Borrelia burgdorferi (22%, 26% and 2030%) and 58% for mycoplasma; similar geographic distribution and improvement in autistic symptoms from antibiotic treatment. It is imperative to research these and all possible causes of autism spectrum disorders in order to prevent every preventable case and treat every treatable case until this disease has been eliminated from humanity.


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