Their goal in this study is to look at “non-toxic treatments for latent persistent forms. Lipids in the form of volatile and non-volatile oils, and fatty acids with proven anti-borreliae efficacy could become another treatment.
Methods
In this study we investigated 47 lipids (30 volatile and non-volatile oils, and 17 fatty acids) of plant and animal origin against typical motile, knob/round-shaped persisters, and biofilm-like Borrelia burgdorferi [Lyme].
Results
Out of all examined lipids, 5 oils:
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Bay leaf oil
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Birch oil
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Cassia oil
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Chamomile oil German
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Thyme oil
…at or below 0.25%,
And 3 fatty acids:
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Docosadienoic acid
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erucic acid
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petroselinic acid
…showed bactericidal activity against typical motile spirochetes [active] and knob/round-shaped persisters.
Only Bay leaf oil and Cassia oil, including their major constituents, eugenol and cinnamaldehyde, showed to target biofilm-like aggregates of both tested Borrelia spp. at the same concentration, although with 20-30% eradication mark.
Conclusion
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Volatile oils were more potent than non-volatile oils
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Unsaturated fatty acids were more effective than saturated fatty acids
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Among all tested oils, Bay leaf oil and Cassia oil, with eugenol and cinnamaldehyde as their major components, seem to have the highest anti-borreliae efficacy
Reference
Goc A, Niedzwiecki A, Rath M. Anti-borreliae efficacy of selected organic oils and fatty acids. BMC Complement Altern Med. 2019 Feb 4;19(1):40. doi: 10.1186/s12906-019-2450-7. PMID: 30717726; PMCID: PMC6360722.