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PROLIFIC LYME LITERATE DOCTOR (MD)
SHARES RESEARCH SUPPORTED HUMAN HERBS

Dr. Schaller treats patients from all over the world. His sessions last 30-180 minutes, and his laboratory testing ranges from 20--65 tests.
He is the author of 60 books and research journal "solutions."
If you are a patient, please read five articles on each treatment.
Please be aware, any medical emails may not be private at your work or home.
This email is confidential and copyrighted.
Dr. Schaller asks you to please inform your family doctor, internist or your child's pediatrician about all treatment.
Please assume Dr. J's approach is not the standard of care.

TOP 50 HERBS BY EVIDENCE SUPPORT

  • A = strongest human evidence
  • B = moderate human evidence
  • C = limited/mixed human evidence
  • D = mostly traditional or preclinical evidence

Herb

Main human use with best support

Rank

1

Peppermint oil (Mentha × piperita)

IBS symptom relief

A

2

Ginger (Zingiber officinale)

Nausea, pregnancy nausea, motion sickness

A

3

Psyllium (Plantago ovata)

Constipation, cholesterol support

A

4

St. John’s wort (Hypericum perforatum)

Mild to moderate depression

A

5

Saw palmetto (Serenoa repens)

BPH urinary symptoms

A/B

6

Milk thistle (Silybum marianum)

Liver support, liver enzyme improvement in some settings

B

7

Turmeric/curcumin (Curcuma longa)

Osteoarthritis pain, inflammation markers

B

8

Garlic (Allium sativum)

Lipids, blood pressure, immune-related outcomes

B

9

Echinacea (Echinacea purpurea)

Common cold prevention/treatment: mixed but usable evidence

B/C

10

Valerian (Valeriana officinalis)

Sleep onset, insomnia

B

11

Chamomile (Matricaria chamomilla)

Mild anxiety, sleep, GI soothing

B

12

Lavender (oral Silexan) (Lavandula angustifolia)

Anxiety symptoms

A/B

13

Cranberry (Vaccinium macrocarpon)

Recurrent UTI prevention

A/B

14

Psyllium + fiber herbs

Bowel regularity, metabolic support

A

15

Artichoke leaf (Cynara scolymus)

Dyspepsia, lipids

B

16

Ashwagandha (Withania somnifera)

Stress, anxiety, sleep, fatigue

B

17

Rhodiola (Rhodiola rosea)

Fatigue, stress-related symptoms

B/C

18

Lemon balm (Melissa officinalis)

Anxiety, sleep, calm

B/C

19

Passionflower (Passiflora incarnata)

Anxiety and sleep

B/C

20

Fenugreek (Trigonella foenum-graecum)

Blood sugar, lactation support

B/C

21

Cinnamon (Cinnamomum verum/cassia)

Glucose control: mixed

C

22

Propolis (bee product, often herbal supplement category)

Oral health, cold symptoms

C

23

Holy basil (Ocimum tenuiflorum)

Stress, glucose, inflammation

C

24

Hawthorn (Crataegus spp.)

Mild heart failure symptoms, circulation

B/C

25

Ginkgo (Ginkgo biloba)

Dementia symptoms, circulation, tinnitus: mixed

B/C

26

Saw palmetto extract combinations

Urinary symptom support

B/C

27

Boswellia (Boswellia serrata)

Osteoarthritis, inflammatory pain

B

28

Devil’s claw (Harpagophytum procumbens)

Low back pain, osteoarthritis

B/C

29

Butterbur (Petasites hybridus)

Migraine prevention, allergic rhinitis

B, but safety-limited

30

Feverfew (Tanacetum parthenium)

Migraine prevention

B/C

31

Black cohosh (Actaea racemosa)

Menopausal symptoms

B/C

32

Red clover (Trifolium pratense)

Menopausal symptoms

C

33

Licorice root (Glycyrrhiza glabra)

Dyspepsia, sore throat, ulcer support

B/C

34

Thyme (Thymus vulgaris)

Cough, bronchitis symptom relief

C

35

Mullein (Verbascum thapsus)

Respiratory soothing

D

36

Oregano (Origanum vulgare)

Antimicrobial claims, digestion

D

37

Sage (Salvia officinalis)

Oral/throat support, sweating

C/D

38

Rosemary (Salvia rosmarinus)

Digestion, cognition: limited human data

C/D

39

Holy basil

Stress support

C

40

Cat’s claw (Uncaria tomentosa)

Inflammation, immune modulation

C/D

41

Astragalus (Astragalus membranaceus)

Immune support, fatigue

C/D

42

Reishi (Ganoderma lucidum)

Fatigue, immune modulation

C/D

43

Cordyceps (Cordyceps spp.)

Exercise tolerance, fatigue

C/D

44

Schisandra (Schisandra chinensis)

Liver/stress support

C/D

45

Nettle (Urtica dioica)

Allergies, inflammation

C

46

Dandelion (Taraxacum officinale)

Digestion, bile support, diuresis

D

47

Burdock (Arctium lappa)

Skin/digestive traditional use

D

48

Calendula (Calendula officinalis)

Topical wound/skin support

C/D

49

Aloe vera (Aloe barbadensis)

Topical burns/skin; oral constipation forms less favored

B/C

50

Arnica (Arnica montana)

Topical bruising/soreness

C

How to interpret this ranking

  • Higher rank = stronger and more consistent human clinical evidence for at least one common use.
  • Some herbs are ranked high because they have good evidence for one specific condition, even if they are not broadly useful for everything.
  • Safety matters: an herb can have evidence but still be inappropriate for some people.

Full references

  1. Black CD, Herring MP, Hurley DJ, O’Connor PJ. Ginger (Zingiber officinale) reduces muscle pain caused by eccentric exercise. J Pain. 2010;11(9):894-903. doi:10.1016/j.jpain.2009.12.013
  2. Viljoen E, Visser J, Koen N, Musekiwa A. A systematic review and meta-analysis of the effect and safety of ginger in the treatment of pregnancy-associated nausea and vomiting. Nutr J. 2014;13:20. doi:10.1186/1475-2891-13-20
  3. Cash BD, Epstein MS, Shah SM. A novel delivery system of peppermint oil is an effective therapy for irritable bowel syndrome symptoms. Dig Dis Sci. 2016;61(2):560-571. doi:10.1007/s10620-015-3858-7
  4. Ford AC, Quigley EMM, Lacy BE, et al. Efficacy of pharmacological therapies for irritable bowel syndrome: systematic review and network meta-analysis. Gut. 2019;68(8):1406-1415. doi:10.1136/gutjnl-2015-311730
  5. Linde K, Berner MM, Kriston L. St John’s wort for major depression. Cochrane Database Syst Rev. 2008;(4):CD000448. doi:10.1002/14651858.CD000448.pub3
  6. Tack J, et al. Peppermint oil in the treatment of irritable bowel syndrome: a systematic review and meta-analysis. J Clin Gastroenterol. 2019.
  7. Levine M, Ludwig A. Herbal medications for common ailments: a review. Am J Med. 2000;108(7):528-536.
  8. Gibb M, et al. Cranberry products for preventing urinary tract infections. Cochrane Database Syst Rev. 2023.
  9. Cameron M, Chrubasik S. Oral herbal therapies for treating osteoarthritis. Cochrane Database Syst Rev. 2014.
  10. 10.Bent S, Padula A, Moore D, et al. Valerian for sleep: a systematic review and meta-analysis. Am J Med. 2006;119(12):1005-1012. doi:10.1016/j.amjmed.2006.02.026
  11. 11.Sarris J, Byrne GJ. A systematic review of insomnia treatments. Sleep Med Rev. 2011.
  12. 12.Ali B, Al-Wabel NA, Shams S, et al. Essential oils used in aromatherapy: a systematic review. Asian Pac J Trop Biomed. 2015;5(8):601-611.

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