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Bransfield’s Lyme Disease And Psychiatric Illness—Summary Table

All impairments were increased postinfection

Total patient group (n=100) pre vs. postinfection

Findings Preinfection, % (95% CI) Postinfection, % (95% CI)
Psychiatric symptoms
Sudden abrupt mood swings 2 (0–6) 80 (69–91)
Exaggerated startle 1 (0–4) 75 (63–87)
Suicidal 1 (0–4) 72 (60–84)
Explosive anger 2 (0–6) 72 (59–84)
Anhedonia 1 (0–4) 71 (58–84)
Nightmares 1 (0–4) 70 (57–83)
Hypervigilance 1 (0–4) 69 (56–82)
Paranoia 0 (0–0) 62 (49–75)
Depersonalization 0 (0–0) 62 (48–75)
Disinhibition 1 (0–4) 58 (44–72)
Hallucinations 1 (0–4) 45 (31–58)
Intrusive images aggressive 2 (0–5) 39 (29–49)
Derealization 0 (0–0) 31 (18–43)
Dissociative episodes 0 (0–0) 25 (13–37)
Intrusive images sexual 1 (0–4) 16 (6–26)
Behavioral symptoms
Marital/family problems 0 (0–0) 64 (51–77)
Legal problems 0 (0–0) 23 (11–35)
Substance abuse 3 (0–8) 22 (10–33)
Psychiatric syndromes 0 (0–0) 0 (0–0)
Depression 3 (0–8) 87 (78–96)
Social anxiety disorder 4 (0–9) 68 (55–81)
Panic disorder 2 (0–6) 66 (53–79)
OCD 2 (0–6) 42 (28–55)
PTSD 4 (0–9) 30 (17–43)
Rapid bipolar 0 (0–0) 19 (8–30)
Cognitive symptoms
Memory impairments 0 (0–0) 87 (78–96)
Processing impairments 0 (0–0) 86 (76–96)
Dyslexia symptoms 2 (0–6) 73 (61–85)
Neurological symptoms
Neuropathy 0 (0–0) 81 (70–92)
Cranial nerve symptoms 0 (0–0) 79 (68–90)
Seizures 0 (0–0) 22 (11–33)
Urogenital
Decreased libido 2 (0–6) 62 (49–75)
Irritable bladder 3 (0–8) 50 (36–64)
Intolerance to alcohol 0 (0–0) 34 (21–47)
Incontinence 2 (0–6) 28 (16–40)
Genital pain 0 (0–0) 28 (16–40)

Abbreviations: CI, confidence interval; OCD, obsessive compulsive disorder; PTSD, posttraumatic stress disorder.

Bransfield RC. Aggressiveness, violence, homicidality, homicide, and Lyme disease. Neuropsychiatr Dis Treat. 2018 Mar 9;14:693-713. doi: 10.2147/NDT.S155143. PMID: 29576731; PMCID: PMC5851570.

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