Can Poor Treatments Like Artemisinin Make You Sicker?
When I first mentioned this weak Artemisia derivative in a book cover, I ignorantly though people would not accept this as a treatment. I foolishly imagined they would read it is weak and may kill some types of malaria—but it does not kill Babesia effectively.
I have inherited many patients who were on very high doses artemisinin for long periods and they still had clearly high volumes of Babesia.
According to Njuguna, the isolation of artemisinin from an ancient Chinese remedy in the early 1970s heralded the beginning of a new era in antimalarial drug therapy culminating in artemisinin-based combination therapies currently being the mainstay of malaria treatment worldwide.
But fast forward to 2012, and the exact chemical Artemisinin specifically is now being rejected internationally as a malaria medication. In the World Health Organization's 2010 Guidelines for the Treatment of Malaria, it is rejected and replaced in virtually every setting.
In many studies, poor treatment like antibiotics and artemisinin are not powerful to kill weak malaria. For example, in a rodent malaria, artemisinin, appears to support more dangerous forms. According to Schneider and Bell in 2012:
In all our treatment ... virulent parasites were less sensitive to pyrimethamine and artemisinin ... Overall, our data suggest that drug treatment can select for more virulent parasites.
Further, Noedl reports the catastrophe of artemisinin resistance:
a race between the development of ever new generations of antimalarial drugs and the emergence of resistance to these antimalarials, finally culminating in the emergence of clinical artemisinin resistance which was first reported in 2008.
One error in some books and practice is people are stuck in the past when artemesinin was possibly more effective, but no good research shows artemisinin is markedly good for Babesia.
Also the expression "artemisinin-based therapies" can mean radically different drugs like artesunate and artemeter. These are not artemisinin.
Genetically determined artemisinin resistance in P falciparum emerged along the Thailand-Myanmar border at least 8 years ago and has since increased substantially. At this rate of increase, resistance will reach rates reported in western Cambodia in 2-6 years.