Dr James Schaller
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Lyme disease, Bartonella & Babesia in Aggression, Rage, Assaults, Violence & Psychiatry — Depression, Panic, Mania, Bipolar, Schizophrenia and Autism

In the last few months, a series of events have caused some to wonder if Lyme disease can cause aggression, assaults, murder, domestic violence and suicide. It is very curious that some actually deny that this is possible since we have known for years that spirochetes like syphilis and the more powerful Lyme spirochete enter and influence the brain in days. Hitler had Syphilis. In addition, many violent and dangerous men in history have acted violently, at least in part, from the impact of this brain infection on their poor baseline personalities.

I typically treat individuals with obvious body illness from independent highly respected labs who show clear abnormal labs, who are told they are cured. Most of these clearly ill children or adults have never been evaluated for Babesia in a manner keeping with 2009 advances, and no one has been competently evaluated for Bartonella, since testers do not know both direct and indirect Bartonella testing. (As the author of 4-5 books on these topics, I feel I have the grounds to be concerned).

In my experience, Bartonella is profoundly agitating and causes all possible psychiatric troubles. Some patients feel like they have gasoline in their veins and are highly reactive and grossly sensitive. I also believe Babesia and Lyme disease, to a lesser extent, can also cause very diverse psychiatric troubles

Role of psychiatric comorbidity in chronic Lyme disease.

OBJECTIVE: To evaluate the prevalence and role of psychiatric comorbidity and other psychological factors in patients with chronic Lyme disease (CLD). METHODS: We assessed 159 patients drawn from a cohort of 240 patients evaluated at an academic Lyme disease referral center. Patients were screened for common axis I psychiatric disorders (e.g., depressive and anxiety disorders); structured clinical interviews confirmed diagnoses. Axis II personality disorders, functional status, and traits like negative and positive affect and pain catastrophizing were also evaluated. A physician blind to psychiatric assessment results performed a medical evaluation. Two groups of CLD patients (those with post-Lyme disease syndrome and those with medically unexplained symptoms attributed to Lyme disease but without Borrelia burgdorferi infection) were compared with 2 groups of patients without CLD (patients recovered from Lyme disease and those with an identifiable medical condition explaining symptoms attributed to Lyme disease). RESULTS: After adjusting for age and sex, axis I psychiatric disorders were more common in CLD patients than in comparison patients (P = 0.02, odds ratio 2.64, 95% confidence interval 1.30-5.35), but personality disorders were not. Patients with CLD had higher negative affect, lower positive affect, and a greater tendency to catastrophize pain (P < 0.001) than comparison patients. All psychological factors except personality disorders were related to level of functioning. A predictive model based on these psychological variables was confirmed. Fibromyalgia was diagnosed in 46.8% of CLD patients. CONCLUSION: Psychiatric comorbidity and other psychological factors distinguished CLD patients from other patients commonly seen in Lyme disease referral centers, and were related to poor functional outcomes.

Hassett AL, Radvanski DC, Buyske S, et al. Arthritis Rheum. 2008 Dec 15;59(12):1742-9. University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, New Brunswick, NJM


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