Dr James Schaller
main page books and articles schaller health creed facebook testimonies search
menu main page what's new second opinion new patient meet doctor schaller location, travel

Ozone and Mold Toxin Destruction

The use of ozone to kill mold and its toxins has been a controversy for years. Opponents correctly remind us that ozone is far more dangerous than carbon monoxide. They shudder when they notice ozone machines running in homes and offices constantly, hurting the body and damaging lungs and causing headaches.

However, one important issue is how a country limits and removes mold toxins from grains, other foods, buildings and schools. This abstract shows that one type of ozone was able to degrade T-2 or trichothecene mold toxins.

Degradation of trichothecene mycotoxins by aqueous ozone.

The degradation of ten trichothecene mycotoxins by aqueous ozone was monitored by liquid chromatography-ultraviolet-mass spectrometry (LC-UV-MS). Saturated aqueous ozone ( approximately 25ppm) degraded these mycotoxins to materials that were not detected by UV or MS. At lower levels ( approximately 0.25ppm) of aqueous ozone, intermediate products were observed. On the basis of UV and MS data, it is proposed that the degradation begins with attack of ozone at the C9-10 double bond with the net addition of two atoms of oxygen. The remainder of the molecule appears to have been left unaltered. The oxidation state at the allylic carbon 8 position had a significant effect on the ease of reaction, as determined by moles of ozone required to effect oxidation. The amount of ozone required to effect oxidation to intermediate products and subsequent degradation followed the series allylic methylene (no oxygen) <hydroxyl (or ester)<keto. Ozonation was also sensitive to pH. At pH 4-6, all mycotoxins studied degraded readily; at pH 7-8 the degree of reactivity was dependent upon the carbon 8 oxidation state; at pH 9, there was little or no reaction. Structures for some of the intermediate products are proposed.

Young JC, Zhu H, Zhou T. Food Chem Toxicol. 2005 Sep 22



Bank Towers, Tamiami Trail, Naples, FL
disclaimer privacy