Lyme Disease Treatment Fails With Common Antibiotics That Only Kill The Active Form
Borrelia afzelii and Borrelia garinii are the leading causes of Lyme borreliosis (LB) in Europe. Persistent LB forms may involve biofilms, potentially contributing to antibiotic tolerance. Methods: Whole-genome sequencing was conducted on 7 B. afzelii and 5 B. garinii isolates from erythema migrans skin biopsies. Biofilms were analyzed for extracellular DNA (eDNA) content… [They looked at the effect of amoxicillin, […]
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