Major Immune-System Changes in Lyme Disease
Yes. Lyme disease does not simply “weaken the immune system.” Borrelia burgdorferi interacts with and alters multiple parts of innate and adaptive immunity. Some responses are strongly activated, while other responses can be diverted, suppressed, or made less effective. The result is an unusual combination of inflammation + immune evasion + incomplete clearance. Strong Innate Immune Activation Borrelia lipoproteins and
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