Binders with Research
“Binders” we define as oral substances that remain largely in the gastrointestinal tract and adsorb, sequester, or ion-exchange specific compounds.
Top 25 environmental exposures associated with autoimmunity Rank Exposure Autoimmune associations Evidence 1 Crystalline silica SSc, RA, SLE, ANCA vasculitis ★★★★★ 2 Cigarette smoke RA, SLE, MS, Graves disease ★★★★★ 3 Trichloroethylene (TCE) Systemic sclerosis, SLE/autoimmune responses ★★★★½ 4 Organic solvents SSc, SLE, MS, systemic autoimmune disease ★★★★ 5 Mercury/methylmercury ANA/autoantibodies; autoimmune dysregulation ★★★★ 6 PM2.5/air pollution RA, CTD, IBD,
TOXINS CREATING AUTOIMMUNITY Continue »
APPENDIX
here is a practical framework for the 50 environmental toxicants. The ratings are comparative—not diagnostic thresholds—and “autoimmune” is deliberately separated from general immune effects because evidence for direct causation of autoimmune disease is much weaker for many chemicals.
COMMON TOXINS HINDERING LYME TREATMENT
TBRF, BARTONELLA, AND BABESIA RECOVERY. Continue »
The strongest evidence supports an overall Mediterranean-style or MIND-style eating pattern, rather than one “superfood.” These patterns emphasize vegetables, fruit, legumes, whole grains, nuts, olive oil, fish, and minimally processed foods while limiting ultra-processed foods, refined carbohydrates, and excessive alcohol.
What food is best for mood and brain health? Continue »
There is a meaningful connection between emotional states, the nervous system, stress hormones, and immune function. But an important clarification is that having a negative emotion for a few hours does not “turn off” your immune system. The strongest evidence concerns persistent or repeated psychological stress and emotional distress, particularly when they disrupt sleep, behavior, cortisol regulation, or social connection.
For your specific goal—immune health + brain health + a healthy gut microbiome—I would build the food list around four overlapping properties:
20 most important ways to support a healthy microbiome 1. Eat a high-fiber diet This is probably the single most important dietary intervention. Gut bacteria ferment dietary fiber into metabolites including acetate, propionate and butyrate, which influence the intestinal environment, epithelial cells and immune system. Full reference: Makki K, Deehan EC, Walter J, Bäckhed F. The Impact of Dietary Fiber on
SUCCESS AND TOP EXPERT LYME DISEASE (LL MD)
CARE REQUIRES A HEALTHY MICROBIOME Continue »
I have coauthored three books on mold. I appreciate the coauthors, Ritchie Shoemaker and Gary Rosen, for teaching me very useful information over 20 years ago. I am not “getting into mold.” I was helping and researching this intensely over 20 years ago. I am glad some are learning in recent years. The Removal of Mycotoxins Requires Immensely Specific Binders.
THE BEST BINDERS FOR MYCOTOXINS. Continue »
25 ways the mammalian body kills or suppresses bacteria 1. Neutrophil phagocytosis Neutrophils recognize, engulf and destroy bacteria inside phagosomes. After engulfment, the phagosome undergoes maturation and acquires enzymes and antimicrobial machinery capable of killing the organism. Neutrophils are among the fastest and most important antibacterial cells in mammals. Reference: Flannagan RS, Cosío G, Grinstein S. Antimicrobial mechanisms of phagocytes
HOW YOUR BODY KILLS LYME DISEASE AND BARTONELLA
TOP VETERAN AUTHOR GIVES EXAMPLES Continue »
Sample Detox Tools 40 Binders / adsorbents / toxin-removal approaches # Binder / treatment What it can bind or remove Human evidence My assessment 1 Activated charcoal Many drugs and organic toxins in the GI tract 🟢 Best-established acute GI adsorbent 2 AST-120 (spherical carbon adsorbent) Indole → indoxyl sulfate and other protein-bound uremic toxins 🟢 Strongest specialized enterosorbent evidence
