Methylene Blue’s Uses With Bartonella, Babesia, and Lyme Disease
According to Feng and colleagues, MB [methylene blue] has significant benefits in treating [Lyme cells that are a hard to kill form that is “frozen”] Borrelia burgdorferi stationary persister cells.
In addition, Ma and colleagues provided evidence of activity against stationary forms of Bartonella, and Li and colleagues showed that MB had significant effects on the stationary and active log phase forms of Bartonella.
Zheng and colleagues reported that MB had relatively low MICs against the log phase form of Bartonella, and was more active than the doxycycline/gentamicin combination against the stationary forms. Lastly, MB and rifampin were the most active agents against the biofilm B. henselae after 6 days of drug exposure.
Given its original use as an antimalarial and similarities in pathophysiology and treatment response between Malaria and Babesia [which does not always apply because Babesia is vastly harder to kill], one could extrapolate that this agent should have anti-Babesia properties. Carvalho and colleagues studied six agents combined with Artusenate [error. In my book on these herb derivatives, I show they mean Artesunate which is powerful and effective worldwide against Babesia in humans for over 23 years based on my research.
Carvalho’s lab studies showed methylene blue was the most powerful drug against strong Babesia bovis.
Summary: Methylene Blue May Have a Role in Killing Bartonella, Lyme Disease, and Babesia. (At Least in the Lab).
MB=methylene blue
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Source
Shor, S.M.; Schweig, S.K. The Use of Natural Bioactive Nutraceuticals in the Management of Tick-Borne Illnesses. Microorganisms 2023, 11, 1759. https://doi.org/10.3390/microorganisms11071759 (opens in new tab)