Trouble if treatment is delayed? YEP.
SAMPLE QUOTES:
1. Lyme has "1000 faces" or vast trouble in the body.
2. Signs and symptoms are "non-specific and polymorph, with multisystemic involvement. Diagnosis is most often one of exclusion..."
3. In untreated "advanced stages are usually resistant to treatment and chronic injuries can occur.
4. Symptoms worsen without treatment and become chronic.
5. She presents after consulting multiple specialists.
6. The authors discuss a 66-year-old woman with a complex history of disease, which began one year prior to admission, through multiple and nonspecific symptoms; she presented herself in numerous medical services (gastroenterology, rheumatology--where an immunosuppressive treatment was initiated, hematology) without receiving a final diagnosis.
She was admitted in our service with altered general state and worsening symptoms, predominantly fever, muscle pain, joint pain, the patient being immobilized in bed.
After multiple investigations and the problem of differential diagnosis with multiple pathologies, we finally established the diagnosis of Lyme disease.
"The peculiarities of the case are represented by the severity of the clinical manifestations and fulminant disease evolution under the unjustified administration of immunosuppressive treatment."
Nat LB, Simiti AL, Poanta LI. Lyme disease. Rom J Intern Med. 2014 Oct-Dec;52(4):269-72. PMID: 25726630.