Depression

In the late 1980s, oncologists began treating cancer patients with pro-inflammatory cytokines called interferon alpha (IFNɑ) and tumor necrosis factor-alpha (TNFɑ)(24). The oncologists noticed something unexpected. A subset of their patients developed severe depression soon after the cytokines were delivered into their patient’s bloodstream (27). One could argue that this is a predictable response. After all, they were diagnosed with cancer and were given what could have […]

Brief research useful findings: Not all metals are pathological. Some are required for proteins, hormones, neurotransmitters, enzymes, etc. Some natural heavy metals have toxic effects, including to the brain. Depression is created or increased by neuron harm or irritation of any kind, including most things you would not detect. Simply, there are many chemicals that can cause neuroinflammation—think gasoline inside

Peptides, small chains of amino acids, play a significant role in regulating your mood and are being studied as a promising area for novel treatments of depression. If an amino acid is a pearl, and the pearl necklace is a protein, a peptide is a modest cluster of the pearls, not 50 pearls or amino acids (that size is a

1. Men are 3-4x more likely to commit suicide. So the notion Depression is largely a female issue is far too simple. Though studies and definitions decades ago listed “female” as a depression “risk factor.” 2. Swetlitz writes helpfully when talking about aloneness: “I was severely depressed for the entirety of my junior year of college. My depression consumed me,

One illusion is that if you complete a residency in psychiatry, you are an expert in treating depression. You do know more than politicians, lawyers, media talk show hosts, or TV physicians, which is a low bar. SAMPLE BASICS 1. Antidepressants grow the brain. Particularly in select important areas. Did you know that? Why do most people not know that?

In an aggressive review article, it was concluded: 1. Ferulic acid was found to significantly improve the depressive-like behaviors of animal models, suggesting it is a potential natural product in the treatment of human depression. 2. It helps the depression brain area grow: * Enhancing monoamine oxidase A (MOA) activity. * Brain microglia activation * Inflammation effects * Impacts anti-oxidative

I was very surprised to learn in 2023 how much research shows antidepressants can grow brain neurons, especially in the hippocampus. Neurogenesis, the process of generating new neurons, is significantly impacted by depression, with impaired neurogenesis in the hippocampus being linked to the development and persistence of depressive disorders. Understanding Neurogenesis Definition: Neurogenesis is the formation of new neurons from