Dr James Schaller
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Fatigue with many other symptoms should humble any health care provider. I am aware of at least twenty causes that are fairly common for chronic fatigue, yet I routinely see health care practitioners and physicians and web sites reporting a "cure."

While some people are helped by some of their products, most do not get "cured" because chronic fatigue is like a fever or irritability — each has many possible causes.

  • The Centers for Disease Control and Prevention (CDC) estimates that as many as half a million people in the US have a Chronic Fatiguing disorder. With the fatigue many patients have personality changes, headache, sleep troubles, moodiness, enlarged or tender lymph nodes and cognitive changes (like a reduced memory or trouble thinking fast).


We live in a time of little psychiatrists who like to call anything they are not able to treat, some psychiatric disorder. These physicians, relatives or "friends" are like little children playing with knives. They are clueless about the hurt they cause and use these labels in ignorant ways.

Dr. Paul Levine, M.D. of the National Institutes of Health writes:

There is general agreement that CFS is a severe debilitating illness that deserves the utmost attention of the clinical and scientific communities.

Among real physicians with some common sense, we can find many other quotes like that of Dr. Levine.

What is the cause of CFS? Right now we seem to have many causes. Here is a sample:

  1. Mycoplasma infections from these under-treated infective agents
  2. Undiagnosed Babesia infections from poppy-seed sized ticks that cause severe fatigue. Routine large national labs rarely find it.
  3. The effect of a very wide range of viruses, which are now dead but have caused body changes, or are still living.
  4. Indoor mold toxins, which are so strong they have been used in war and are so toxic, that they are not able to be used in chemotherapy to kill cancer.
  5. Lyme disease — the common symptoms of CFS are all found with Lyme, which is found in every state and is routinely missed because the marks and symptoms people expect are simplistic — you can have no clear mark on your skin and one of three hundred symptoms.
  6. Hormonal abnormalities. The number of hormones that can be abnormal is too large for this article. But just to be clear, if your blood testing consists of four blood tubes they are hardly testing for all the many hormones that can be associated with fatigue. For example, an MSH level, which is a hormone with twenty roles in the body, should be tested by LabCorp, which has good accuracy.
  7. Inflammation irregularities. The inflammation system is like a bike wheel with many parts that must be in balance or centered. Just like spokes on a wheel the inflammation systems and the anti-inflammation systems need to be balanced for health.
  8. Brain protein abnormalities. One study looked at spinal fluid that washes over the brain, and found these proteins, alpha-1-macroglobulin, amyloid precursor-like protein 1, keratin 16, orosomucoid 2 and pigment epithelium-derived factor to be abnormal.
  9. Twin studies show some contribution of genetics
  10. Abnormal immune function which at times will include auto-immunity with parts of the immune system acting dysfunctionally.
  11. Nutritional abnormalities
  12. Disorders of ATP production. ATP is nothing complex, it is simply the gasoline chemical of the body. What is tricky is that many chemicals are involved in some part of ATP production, so limiting it to one protein is unlikely. Some of these have large names that will put most patients to sleep. Samples are: Vasoactive neuropeptides like pituitary adenylate cyclase activating polypeptide (PACAP), calcitonin gene related peptide (CGRP) and vasoactive intestinal peptide (VIP). Each of these seems to be found to be abnormal in some patients with chronic fatigue.
  13. Finally, as we reach our denser possible causes out of hundreds, we enter the world of G proteins. While they sound like a fashion statement — "G protein wear," they have many roles. G protein-coupled receptors (GPCRs) are involved with a huge number of the key receptors in the body. Receptors are big in the human bodies functioning, and anything that undermines them affects energy. G proteins are involved with the effect of nucleotides, catecholamines, calcium, histamine, serotonin and prostaglandins in the body.

We could go on, but the point of this little exercise is:


And if you are told some herb or nutrient has some ability to cure you, if you think it is that simple, compare the cost, potency and standardization with the wholesale prices off this site. Or bypass my link and go directly to vitacost.com

I believe in cures, but not simplistic ones.

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