Dr. James Schaller, MD
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Title: Use of Special T3 or a Non-Synthroid Form of Thyroid to Help Depression and Fatigue

When you talk to someone about thyroid they immediately think of Synthroid. Synthroid has controlled the thyroid market for years and the education around thyroid use.

Yet one of the great findings in psychiatry is that raising people with normal thyroid levels into higher normal thyroid levels can help depression with a Non-Synthroid form of thyroid.

I like to use IQ as an analogy: an IQ of 80 is normal and so is 120 (100 is average). But if I had a choice I would prefer to be closer to 120 in my IQ than 80.

Our research has found that in measuring freeT3 levels is very telling to patients. Most women who reach 40 years old start to slowly drift down in their freeT3 level. Why does this matter?

T4 is generally a pre-hormone with only a few uses. The real deal is T3--a form of thyroid which is 8-10 times more potent than T4.

As some people age, especially women, they start to have a decrease in their usable or "free" T3 and this may make them more likely to become tired, cold or depression.

Most labs done in routine exams of a few tubes do not test for the level of "free" or usable potent T3 thyroid in your body.

I was very troubled to see that some state boards of medicine seem to have trouble reading medical journals and are harassing smart physicians who use T3 as a treatment. They seem to be oblivious to the fact that we have proven in psychiatry repeatedly that for some aspects of depression, T3 works better than Synthroid (T4), which is merely a pro-hormone. Unfortunately, as has been proven in recent years in our leading medical journals, drug companies have primary control of medical research and data presentation to doctors. What unfortunate tunnel vision.

Unfortunately, some state boards actually think the only ones who look at hormones are endocrinologists. Hardly. Every physician has the option of mastering some aspect of hormones if they are inclined to spend the time. Since medical articles in one database alone number over 11 million, it is silly to think anyone can master any specialty.

And also of note, are two articles in recent years, one from the New England Journal of Medicine and one from a respected Cardiology Journal, with both reporting that the presence of some added T3 improved patient health and function.

It is good to know after all these years, our colleagues realize the psychiatrists had it right all along.

Wishing you much health!

Dr. James Schaller


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