Title: Natural Progesterone Cream for Premenstrual Dysphoric Disorder, Journal of the American Academy of Child and Adolescent Psychiatry

In contrast to the marketing of serotonin medications like Prozac (Sarafem) and Zoloft, we have found that the best treatment for premenstrual symptoms is natural progesterone.

In the second half of the menstrual cycle, calming progesterone can be overwhelmed by high levels of estrogen. Excess estrogen can come from fat estrogen and the natural decline in progesterone after about age 34.

If you have excess estrogen you get excess water all over the body-- that feels bad. Natural progesterone helps you pee off this excess fluid. It is naturally sedating and calming. Natural progesterone is not to be confused with synthetic super steroids called progestins. Many studies and people confuse the real thing with an artificial thing -- they work very differently. For example, synthetic progesterone prevents pregnancy and natural progesterone increases fertility.