Does Neurotropin® Help Pain, CFS and Fibromyalgia?

Neurotropin® is a drug manufactured by Nippon Zoki Pharmaceutical Co., Ltd. The drug is available in Japan and China and is used to treat diseases associated with pain such as eccentric coldness, numbness, lumbago and shoulder, arm and neck syndrome mainly in the fields of surgery, orthopedic surgery, and anesthesia. NIH and other international agencies are looking at its use for chronic neuropathic pain and tooth extraction pain, and for reflex sympathetic dystrophy pain. It is available for injection and in tablet form.

Efficacy of neurotropin in
chronic fatigue syndrome: a case report.

Chronic fatigue syndrome (CFS) is a disorder that causes general fatigue and chronic widespread pain. A 28-year-old male visited an outpatient department due to general fatigue and pain involving the entire body. He did not suffer from fibromyalgia, but he was diagnosed with CFS. At the initial visit, he complained of lack of concentration, memory decline, frequent urination, insomnia and occasional difficulty of emotional control, as well as general fatigue and pain involving the entire body. Four tablets of Neurotropin per day alone were administered. General fatigue and pain were gradually alleviated one week later. His sleep condition, concentration power, and memory also improved two weeks later. Medication was discontinued from 11 weeks based on the patient's judgment as he felt little general fatigue and pain involving the entire body. Treatment was completed 3 months later. The symptoms disappeared and did not recur five months after the discontinuation of Neurotropin. He was looking for a job without fatigue and pain 8 months later (5 months after the cessation of treatment). The functional mechanisms of Neurotropin in CFS are unknown.

Toda K, Kimura H. Hiroshima J Med Sci. 2006;55:35-7. PMID: 16594551

www.clinicaltrials.gov/ct/show/NCT00006289