Lyme Disease is Not Easily Killed:
Some Sample Articles to Support the Clinically Obvious

Abstracts on the persistence of Lyme.

• A proposal for the reliable culture of Borrelia burgdorferi from patients with chronic Lyme disease, even from those previously aggressively treated
• Antibodies against whole sonicated Borrelia burgdorferi spirochetes, 41-kilodalton flagellin, and P39 protein in patients with PCR- or culture-proven late Lyme borreliosis
• Borrelia burgdorferi detected by culture and PCR in clinical relapse of disseminated Lyme borreliosis
• Borrelia burgdorferi myositis: report of eight patients
• Chronic neurologic manifestations of Lyme disease
• Chronic septic arthritis caused by Borreliaburgdorferi
• Clinical implications of delayed growth of the Lyme borreliosis spirochete, Borrelia burgdorferi
• Clinical manifestations, pathogenesis, and effect of antibiotic treatment on Lyme borreliosis in dogs.
• Cultivation of Borrelia burgdorferi from joint fluid three months after treatment of facial palsy due to Lyme borreliosis
• Detection of Borrelia burgdorferi Antigen in Urine from Patients with Lyme Borreliosis
• Detection of Borrelia burgdorferi antigens in cerebrospinal fluid
• Detection of Borrelia burgdorferi by polymerase chain reaction in synovial membrane, but not in synovial fluid from patients with persisting Lyme arthritis after antibiotic therapy
• Detection of Borrelia burgdorferi DNA by polymerase chain reaction in synovial fluid from patients with Lyme arthritis
• Diagnostic Hints and Treatment Guidelines for Lyme and Other Tick Borne Illnesses
• Electron microscopy and the polymerase chain reaction of spirochetes from the blood of patients with Lyme disease
• Evidence-based guidelines for the management of Lyme disease
• Experimental Lyme disease in dogs produces arthritis and persistent infection
• Fatal adult respiratory distress syndrome in a patient with Lyme disease
• Fatal encephalitis caused by concomitant infection with tick-borne encephalitis virus and Borrelia burgdorferi
• Fibroblasts protect the Lyme Disease spirochete, Borrelia burgdorferi from ceftriaxone in vitro
• First isolation of Borrelia burgdorferi from an iris biopsy
• Formation and Cultivation of Borrelia burgdorferi Spheroblast-L Form Variants
• Inflammatory brain changes in Lyme borreliosis
• Intracellular localization of Borrelia burgdorferi within human endothelial cells
• Invasion of human skin fibroblasts by the Lyme disease spirochete, Borrelia burgdorferi
• Invasion of the central nervous system by Borrelia burgdorferi in acute disseminated infection
• Isolation of Borrelia burgdorferi from the myocardium of a patient with longstanding cardiomyopathy
• Isolation of Borrelia burgdorferi in the cerebrospinal fluid of 3 children with neurological involvement
• Kill kinetics of Borrelia burgdorferi and bacterial findings in relation to the treatment of Lyme borreliosis
• Latent Lyme neuroborreliosis: presence of Borrelia burgdorferi in the cerebrospinal fluid without concurrent inflammatory signs
• Localization of Borrelia burgdorferi in the nervous system and other organs in a nonhuman primate model of Lyme disease
• Lyme arthritis in a 12-year-old patient after a latency period of 5 years
• Lyme borreliosis--a review of the late stages and treatment of four cases 
• Lyme Disease: An Infectious and Postinfectious Syndrome 
• Lyme disease: point/counterpoint.
• Lyme disease: The sensible pursuit of answers
• Lyme meningoencephalitis: report of a severe, penicillin-resistant case.
• Molecular detection of persistent Borrelia burgdorferi in a man with dermatomyositis
• Neuroborreliosis in the nonhuman primate: Borrelia burgdorferi persists in the central nervous system
• Pars plana vitrectomy in Borrelia burgdorferi endophthalmitis
• Persistence of Borrelia burgdorferi in experimentally infected dogs after antibiotic treatment
• Persistence of Borrelia burgdorferi in ligamentous tissue from a patient with chronic Lyme Borreliosis
• Persistence of Borrelia burgdorferi sensu lato in patients with Lyme borreliosis
• Persistence of Borrelia burgdorferi sensu lato in resolved erythema migrans lesions.
• Persistence of Borrelia garinii and Borrelia afzelii in patients with Lyme arthritis
• Persistence of Organisms for Lyme Arthritis
• Persistent PCR Positivity in a patient being treated for Lyme disease
• Physician Preferences in the Diagnosis and Treatment of Lyme Disease in the United States
• Pulsed high-dose cefotaxime therapy in refractory Lyme Borreliosis
• Randomized comparison of ceftriaxone and cefotaxime in Lyme neuroborreliosis
• Recurrent and relapsing borreliosis of the nervous system
• Recurrent erythema migrans despite extended antibiotic treatment with minocycline in a patient with persisting Borrelia burgdorferi infection
• Seronegative Chronic Relapsing Neuroborreliosis
• Spirochetes in the spleen of a patient with chronic Lyme disease
• Subacute multiple-site osteomyelitis caused by Borrelia burgdorferi
• Successful treatment of Lyme encephalopathy with intravenous ceftriaxone
• Survival of Borrelia burgdorferi in antibiotically treated patients with Lyme borreliosis
• The fate of Borrelia burgdorferi in mouse macrophages: destruction, survival, recovery
• The long-term clinical outcomes of Lyme disease. A population-based retrospective cohort study
• The Lyme Wars: time to listen
• The persistence of spirochetal nucleic acids in active Lyme arthritis
• The western immunoblot for Lyme disease: determination of sensitivity, specificity, and interpretive criteria with use of commercially available performance panels
• Treatment of Late Lyme Borreliosis
• Treatment of refractory chronic Lyme arthritis with arthroscopic synovectomy

Dr. Schaller and Lyme Disease Action are not responsible for the contents or able to endorse any abstract. The accuracy of this material is strictly limited to the authors publishing this material.

Reprinted with written permission of Lyme Disease Action

Source:www.lymediseaseaction.org.uk/articles/persistence.htm