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Lyme Disease:Clear Effects on Mood,
Functioning, Aggression, Behavior, Learning
and Mental Health

Lyme disease patients can experience many psychiatric and neurological symptoms. Any psychiatric, personality or neurologic disorder can be directly caused by entirely by "The Great Imitator"---Lyme.

It is common for Lyme to directly cause attention problems, short-term memory loss, depression, panic attacks, personality changes, mood swings, mania, aggression, and/or learning disabilities. Some introductory literature on these manifestations is found below.


Sample Materials:

Distinct pattern of cognitive impairment noted in study of Lyme patients

by Marian Rissenberg, Ph.D. & Susan Chambers, M.D.
The Lyme Times, Vol. 20, January-March 1998, pp. 29 -32
SUMMARY:
The following items are covered: Cognitive Characteristics of Chronic Lyme Encephalopathy, Neuropsychological deficits, Possible Pathophysiologic Mechanisms of Cognitive Impairment in Lyme Disease, Clinical Impressions and Implications for Diagnosis and Treatment in Chronic Lyme Disease, Cognitive impairment in Lyme disease: specific functions and the impact or deficits.

The Neuropsychiatric Assessment of Lyme Disease

by Robert Bransfield, M.D.
SUMMARY:
"From a combination of clinical experience, journal review, and discussion with colleagues, a structured interview was developed" to assist in the overall clinical assessment when late state Lyme disease is suspected. Additional material is available at the same website. SEE: Mental Health and Illness .Com

Overview of Neuropsychiatric Lyme Disease

Columbia University Lyme Website
SUMMARY:
The following items are covered: Typical time course, symptoms, cognitive and psychiatric aspects for both children and adults.

Bibliography of Neuropsychiatric Lyme

A collection of references to medical/scientific literature on psychiatry and Lyme/tick-borne disease. One item worth obtaining the full-text of is "The Neuropsychiatric Manifestations of Lyme Borreliosis".


Full Text Peer-Reviewed Articles

The following articles, listed alphabetically, are available online at no charge. Additional peer-reviewed articles are listed in the bibliography above, and some of those may be worth obtaining through your medical library.

A Controlled Study of Cognitive Deficits in Children With Chronic Lyme Disease (pdf file)

Tager, Fallon, et. al.
J Neuropsychiatry Clin Neurosci 13:500-507, November 2001

Functional Brain Imaging and Neuropsychological Testing in Lyme Disease (pdf file)

by Fallon, Das, Plutchok, Tager, Liegner, Van Heertum
CID 1997; 25:S57-63
(Requires Adobe Acrobat)

Higher Prevalence of Antibodies to Borrelia Burgdorferi in Psychiatric Patients Than in Healthy Subjects

by Hajek, et. el.
Am J Psychiatry 159:297-301, February 2002

Late-Stage Neuropsychiatric Lyme Borreliosis: Differential Diagnosis and Treatment

by Fallon, et. al.
Psychosomatics 1995;36:295-300

Lyme Disease: A Neuropsychiatric Illness

by Fallon, Nields
Am J Psychiatry 151:11, November 1994 pp.1571-1580

Musical Hallucinations in Patients with Lyme Disease

by Stricker, Winger
Southern Medical Journal 2003; 96(7):711-715

The neuropsychiatric manifestations of Lyme borreliosis

by Fallon, Nields, Burrascano, Liegner, DelBene, Liebowitz
Psychiatr Q 1992 Spring;63(1):95-117
**RECOMMENDED ITEM

The Physician as a Patient: Lyme Disease, Ehrlichiosis, and Babesiosis: A Recounting of a Personal Experience with Tick-Borne Diseases

by Sherr
Practical Gastroenterology, January 2000

Potential uses of Modafinil in Psychiatric Disorders (pdf file)

by Bransfield
Journal of Applied Research, 2004 Spring; 4(2): 198-208
(Requires Adobe Acrobat)

For insurance, see: Forms 1 and Forms 2

Seasonal correlation of sporadic schizophrenia to Ixodes ticks and Lyme borreliosis

by Fritzsche
International Journal of Health Geographics 2002 1:2

The Underdiagnosis of Neuropsychiatric Lyme Disease in Children and Adults

by Fallon, Kochevar, Gaito, Nields
Psychiatric Clinics of North America, 1998; 21: 693-703


Misc. Articles (News, Newsletters, Websites, etc.)

Articles By Robert Bransfield, M.D.

Lyme Alliance Newsletter
The following articles are available: "All in Your Head?", "Microbes and Mental Illness", "Spirochetes On the Brain", "Lyme Disease and Cognitive Impairments", "Lyme, Depression, and Suicide", "Agression and Lyme Disease", "A Tale of Two Spirochetes" and "Sex and Lyme Disease". The following are the most recently added: "Gettysburg Times Article", "The Klempner Study", "Posttraumatic Stress Disorder and Infectious Encephalopathies", "The Psychotropic Management of Late-Stage Lyme and Associated Diseases" and "What Causes Illness and Mental Illness?".

Understanding the Puzzle of Chronic Lyme

Columbia University Medical Center News, August 2004

Brain Scans Distinguish Lyme Disease From Primary Psychiatric Disorders

Doctor's Guide to the Internet, October 24, 1997

Can Lyme Disease Cause Psychiatric Disorders?

by Joan Arehart-Treichel
Psychiatric News: March 15, 2002

Teen Angst or Depression?

Seattle Post-Intelligencer: October 2002

Neurological Impairment Seen in Patients Given Lymerix

DG News: October, 2002

I Refused to Give Up on My Daughter

Good Housekeeping: October 2003

Lyme Signs Missed

by James Schaller, MD

Psychological and Neurological Basic Findings of Active Lyme Disease

by James Schaller, MD

Actress with Migraines and ADD Reports Both Due to Lyme

by James Schaller, MD

Cognition Problems Fuel Lyme Disease Debate

by Nancy Walsh
Clinical Psychiatry News: October 2002
Free Registration Required

Lyme disease victims find new hope in study on Cape

Cape Cod Times: November 2002
Free Registration Required

Amy Tan, Ticked Off About Lyme

Washington Post, August 2003

A Disease in Disguise

Newsweek: August, 2004

Diseases of the Mind

Newsweek International: December 2003

Brain Imaging

Columbia University Lyme Website

Treatment of Lyme Disease

Columbia University Lyme Website

Lyme Disease and Psychiatric Disorders

P&S Journal: Winter 1998, Vol.18, No.1


Presentations

Psychiatric and neuropsychological aspects of Lyme Disease

by Felice A. Tager, Ph.D. and Brian A. Fallon, M.D.
Meeting of the American Psychiatric Association, May 2002

Testimonies of Brian Fallon, M.D. and Carolyn Britton, M.D.

NY Assembly Health Committee Hearing on Lyme Disease
November, 2001 (Scroll down)

Testimony of Robert Bransfield, M.D.

NY Assembly Health Committee Hearing on Lyme Disease
November, 2001

Spirochetes may "love the brain to death"

by Dr. Diego Cadavid
101st General Meeting of the American Society for Microbiology, May, 2001.

Neurologic Lyme Disease: Defining and Treating an Elusive Target

by Brian A. Fallon, M.D., and Harry Goldhagen, MS
14th International Scientific Conference on Lyme Disease & Other Tick-Borne Disorders, April, 2001.
(Free Registration Required)

Review of Lyme Neuroborreliosis

13th International Scientific Conference on Lyme Disease and other Tick-borne Disorders, March, 2000.

Lyme Neuroborreliosis: Recognition, Treatment, and Retreatment of Relapse

13th International Scientific Conference on Lyme Disease and other Tick-borne Disorders, March, 2000.

Cognitive Remediation

by Leo Shea, PhD
12th International Conference on Lyme Disease and Other Spirochetal and Tick-Borne Disorders, April 1999.
Also See: presentation abstract

Summary of Neurologic Lyme Disease Presentations

by Brain A. Fallon, M.D.
12th International Conference on Lyme Disease and Other Spirochetal and Tick-Borne Disorders, April 1999.

Lyme Disease vs. Somatoform Disorders

by Brian A. Fallon, M.D.
10th Annual International Scientific Conference on Lyme Disease & Other Tick-Borne Disorders, April 1997.

Psychiatric Aspects of LD & the Use of SPECT Imaging

by Brian A. Fallon, M.D.
10th Annual International Scientific Conference on Lyme Disease & Other Tick-Borne Disorders, April 1997.

Seronegative Chronic Meningoencephalomyelitis in LD

by Kenneth B. Liegner, M.D.
10th Annual International Scientific Conference on Lyme Disease & Other Tick-Borne Disorders, April, 1997.

Lyme Disease and the Clinical Spectrum of Antibiotic-Responsive Chronic Meningoencephalomyelitides

by Kenneth B. Liegner, M.D.
9th Annual International Scientific Conference on Lyme Disease & Other Tick-Borne Disorders, April, 1996.

Lyme Disease vs. Depression vs. Somatization: Cognitive Tests & Functional Imaging

by Brian A. Fallon, M.D.
9th Annual International Scientific Conference on Lyme Disease & Other Tick-Borne Disorders, April 1996

Neurofeedback and Lyme Disease: A Clinical Application of the Five Phase Model of CNS Functional Transformation

by Valdeane Brown, Ph.D.
Annual Conference of the Society for the Study of Neuronal Regulation, May 1995


Books & Videos:

Neuropsychiatric Aspects of Other Infectious Diseases.

By Brian A. Fallon, M.D.
Comprehensive Textbook of Psychiatry., Ed. Kaplan and Sadock. Williams & Wilkins, 2002.

Lyme & Other Tick-borne Diseases: A 21st Century View, 2001

Neuropsychiatric Lyme Disease Update by Brian A. Fallon, M.D.
Neurological Manifestations of Lyme Disease by Richard S. Rhee, MD

Neuropsychiatric Manifestations of Lyme Borreliosis

by Brian A. Fallon, M.D.
Columbia University Lyme Website


Additional Resources:

Medical Literature Summaries

In particular, the symptoms file has information pertaining to neuropsychiatric Lyme. The Neurologic system begins on page 17 of the symptoms file.

Journal Articles

A Selection of Free Journal Articles Available Online on the subject of Lyme and Other Tick-Borne Diseases.

Lyme slide show

SPECT perfusion images

The Whole Brain Atlas

SPECT Scans

Neurological Testing Procedures

Not Lyme-specific

Neuropsychological Testing

Not Lyme-specific

Neuropsychiatric Lyme Page

By Kay

Annotated Bibliographies

Art Doherty's "Annotated Bibliographies of Medical and Scientific Articles on Lyme Disease Issues".

Other Diseases/Conditions and Lyme Disease

by Art Doherty

Lyme Disease and Bipolar Disorder

by Art Doherty

Lyme Disease and Neurological Manifestations

by Art Doherty

Lyme Disease and Sleep Disorders

by Art Doherty

 

While this is not a complete list of the clinical findings of psychiatrists and child psychiatrists working with struggling patients, it is a solid introduction. If you have further specific questions, feel free to do an email or phone consult.

I would like to thank Cheryl at www.lymeinfo.net for her massive sacrifice of time and money to establish one of the most useful Lyme education sites in the world. It is profoundly superior to the poverty of information the CDC offers.

She has networked with physicians who have treated more Lyme patients than probably the entire CDC staff combined, and offers material that most infectious disease experts would do well to read so they are not back in the 1990's. Most infectious disease doctors are not just missing Lyme every day, but are actively opposing the best care for the number one vector illness in the USA--Lyme. Currently, they use junk labs, ignore dangerous co-infections, attack physicians who fix their failures, have poor clinical observation powers for tick illness, and almost caused me to lose many family members and friends who had massive symptoms--they almost died! These physicians were following a few famous "leaders" in Lyme ultra-conservative treatment and the silly CDC approach to Tick disease. The good news is the CDC usually gets it eventually. But some folks do not live long enough to see their enlightenment.

In conclusion, let me offer a sober warning. I have seen some Lyme infected people do violent, addictive and impulsive things that do not reflect the person, but their brain infection. Please get them treated. Now.



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