The use of d-ribose in chronic fatigue syndrome
and fibromyalgia: a pilot study.
Objectives: Fibromyalgia (FMS) and chronic fatigue syndrome (CFS) are debilitating syndromes that are often associated with impaired cellular energy metabolism. As D-ribose has been shown to increase cellular energy synthesis in heart and skeletal muscle, this open-label uncontrolled pilot study was done to evaluate if D-ribose could improve symptoms in fibromyalgia and/or chronic fatigue syndrome patients. Design: Forty-one (41) patients with a diagnosis of FMS and/or CFS were given D-ribose, a naturally occurring pentose carbohydrate, at a dose of 5 g t.i.d. for a total of 280 g. All patients completed questionnaires containing discrete visual analog scales and a global assessment pre- and post-D-ribose administration. Results: D-ribose, which was well-tolerated, resulted in a significant improvement in all five visual analog scale (VAS) categories: energy; sleep; mental clarity; pain intensity; and well-being, as well as an improvement in patients' global assessment. Approximately 66% of patients experienced significant improvement while on D-ribose, with an average increase in energy on the VAS of 45% and an average improvement in overall well-being of 30% (p < 0.0001). Conclusions: D-ribose significantly reduced clinical symptoms in patients suffering from fibromyalgia and chronic fatigue syndrome.
Teitelbaum JE, Johnson C, Cyr JS. J Altern Complement Med. 2006 Nov;12(9):857-62
I have been surprised to see the high prices offered for this treatment. On this site we offer published wholesale to patient prices. Shop and compare and check for quality.
On my site we offer 3 grams per serving and 200 capsules for $23.99, not $69.00. We also offer 5 gram servings (10.6 ounces) in 300 gram bottles for $27.99, not $69!